If you’re craving a homey, comforting meal that truly embodies rich flavors and layered goodness, you’ve got to try this Southern Five-Layer Beef Casserole Recipe. It’s the kind of dish that fills your kitchen with the warm aroma of spiced beef, creamy cheese, and tender potatoes, cleverly stacked to create a hearty and satisfying dinner. Each layer adds a unique texture—from savory, juicy beef to smooth, cheesy potato slices—making every bite a delightful celebration of Southern-style cooking at its finest.

Southern Five-Layer Beef Casserole Recipe - Recipe Image

Ingredients You’ll Need

These ingredients are straightforward but essential for building those delicious layers. Each one plays an important role in bringing texture, flavor, and color to your Southern Five-Layer Beef Casserole Recipe, ensuring it tastes like a true classic.

  • 1 lb ground beef: The savory backbone of the dish, providing rich and hearty flavor.
  • 1 small onion, chopped: Adds sweetness and depth when sautéed with beef.
  • 2 cloves garlic, minced: Infuses the beef with subtle aromatic warmth.
  • 1 tbsp olive oil: Perfect for gently cooking the beef mixture without overpowering.
  • 1 can (10.5 oz) cream of mushroom soup: Adds creamy moisture and earthiness to the beef layer.
  • 1 can (10 oz) diced tomatoes with green chilies: Brings a tangy, slightly spicy kick for amazing flavor contrast.
  • 1 tsp salt: Enhances all the flavors in every layer.
  • ½ tsp black pepper: Adds mild heat and complexity.
  • ½ tsp paprika: Introduces a smoky subtlety that ties all tastes together.
  • 3 large potatoes, peeled and thinly sliced: Provide tender, hearty layers that soak up the flavors beautifully.
  • 1 ½ cups shredded cheddar cheese: Melts bubbly on top and between layers for rich creaminess.
  • ½ cup sour cream: For a final creamy touch and tangy richness on top.
  • Fresh parsley, chopped (for garnish): Adds a pop of fresh color and brightness.

How to Make Southern Five-Layer Beef Casserole Recipe

Step 1: Prepare Your Oven and Baking Dish

Start by preheating your oven to 375°F (190°C) and greasing a 9×13-inch baking dish. Getting your oven ready ensures your casserole cooks evenly, while greasing prevents sticking and helps with easy serving.

Step 2: Cook the Beef Mixture

Heat olive oil in a skillet over medium heat, then add the ground beef, chopped onion, and minced garlic. Cook everything until the beef is fully browned and aromatic, then drain the excess fat for a lighter, cleaner taste. This step builds the hearty foundation for your casserole’s layers.

Step 3: Add Soup, Tomatoes, and Seasonings

Stir in the cream of mushroom soup and diced tomatoes with green chilies, then season the mixture with salt, black pepper, and paprika. Let it simmer gently for about 5 minutes to allow those flavors to meld perfectly—this gives the beef layer that classic Southern comfort flavor you’re craving.

Step 4: Layer the Potatoes

Arrange half of the thinly sliced potatoes evenly at the bottom of your greased baking dish. These form the first comforting base layer that holds everything together and provides a tender, satisfying texture beneath the beef mixture.

Step 5: Add the First Beef Layer

Spoon half of the savory beef mixture over the potatoes in an even layer. This is where the magic starts to come alive, as the juicy beef mingles with the potatoes below.

Step 6: Sprinkle with Cheese

Generously sprinkle ½ cup of shredded cheddar cheese evenly over the beef layer. The cheese melts into gooey pockets that add richness and a satisfying bite.

Step 7: Repeat Potatoes and Beef Layers

Place the remaining potatoes over the cheese, followed by the rest of the beef mixture on top. Layering again ensures every portion of this casserole has that perfect balance of tender potatoes and flavorful beef.

Step 8: Top with Remaining Cheese

Finally, sprinkle the last half cup of shredded cheddar cheese on top. This creates a golden, bubbly crust that looks inviting and tastes incredible.

Step 9: Bake Covered

Cover the dish with foil and bake in the oven for 45 minutes. Covering protects the moisture in the casserole, allowing the potatoes to cook through perfectly without drying out.

Step 10: Uncover and Finish Baking

Remove the foil and bake for an additional 10 to 15 minutes until the cheese has melted beautifully and the potatoes are tender when pierced with a fork. This step gives you that irresistible cheesy top layer everyone loves.

Step 11: Rest Before Serving

Let the casserole rest for about 5 minutes after baking. This resting period helps the layers settle and makes scooping servings much easier without everything falling apart.

Step 12: Add Sour Cream and Parsley

Top each serving with a dollop of sour cream and sprinkle with fresh parsley. These finishing touches add creamy tang and fresh color that elevate the dish’s presentation and flavor.

How to Serve Southern Five-Layer Beef Casserole Recipe

Southern Five-Layer Beef Casserole Recipe - Recipe Image

Garnishes

Adding a dollop of sour cream and a sprinkle of fresh parsley right before serving provides a delightful tang and vibrant green contrast against the cheesy, golden casserole. It’s a simple step that makes your dish feel special and restaurant-worthy.

Side Dishes

Pair this rich casserole with crisp green beans or a simple mixed salad to balance the meal. A slice of buttery cornbread or warm dinner rolls also complements the Southern vibe beautifully, helping soak up every last bit of sauce.

Creative Ways to Present

Serve the casserole in individual ramekins for a personal touch, or bake and present it family-style in the dish for sharing. You can also experiment by adding a sprinkle of chopped scallions or a dash of smoked paprika on top just before serving to highlight the flavors and presentation.

Make Ahead and Storage

Storing Leftovers

Once cooled, cover your leftover Southern Five-Layer Beef Casserole tightly with plastic wrap or transfer it to an airtight container. Stored properly in the refrigerator, it will stay delicious for up to 3 days, making it great for next-day lunches or easy dinners.

Freezing

This casserole freezes well, making it perfect for batch cooking. Wrap the dish tightly with foil and then plastic wrap or transfer portions into freezer-safe containers. It will keep for up to 2 months without losing its wonderful flavors and texture.

Reheating

Reheat leftovers covered with foil in a 350°F (175°C) oven for about 20 minutes until heated through. You can also reheat single portions in the microwave—just be sure to cover loosely to retain moisture and avoid drying out the potatoes.

FAQs

Can I use a different type of cheese?

Absolutely! While cheddar cheese is traditional and lends a sharp, creamy flavor, you could try Monterey Jack, Colby, or even a smoky Gouda for a different twist. Just make sure it melts well to keep the cheesy layers gooey and delicious.

Is there a vegetarian version of this casserole?

Yes! You can easily substitute the ground beef with cooked lentils, mushrooms, or a plant-based meat alternative. Use vegetable broth in place of beef seasoning to keep those rich flavors and follow the same layering technique.

Can I prepare this casserole ahead of time and bake later?

Definitely. Assemble the casserole up to step 8, then cover tightly and refrigerate for up to 24 hours before baking. This makes your Southern Five-Layer Beef Casserole Recipe perfect for busy days or meal prep.

What if I don’t have cream of mushroom soup?

No worries! You can make a quick homemade substitute by mixing sour cream or cream cheese with a bit of milk and sautéed mushrooms. This keeps that creamy texture and flavor without needing the canned soup.

Can I add other vegetables to the casserole?

Of course. Diced bell peppers, corn, or green beans can be mixed into the beef mixture for extra nutrition and color. Just be mindful of moisture content to keep the casserole from becoming too soggy.

Final Thoughts

This Southern Five-Layer Beef Casserole Recipe is truly one of those meals that brings pure comfort and joy to the table. Whether you’re feeding a family or just want something hearty and delicious on a cozy night in, this casserole delivers in every way. It’s easy to make, full of flavors that remind you of warm Southern hospitality, and perfect for sharing with loved ones. Give it a try soon—you’ll understand why it quickly becomes a favorite in any home.

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Southern Five-Layer Beef Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 3.9 from 25 reviews
  • Author: admin
  • Prep Time: 15 minutes
  • Cook Time: 1 hour
  • Total Time: 1 hour 15 minutes
  • Yield: 6 servings
  • Category: Casserole
  • Method: Baking
  • Cuisine: Southern American

Description

A hearty and comforting Southern Five-Layer Beef Casserole that combines layers of seasoned ground beef, thinly sliced potatoes, creamy mushroom soup, and melted cheddar cheese. This casserole is baked until golden and bubbly, then topped with sour cream and fresh parsley for a delightful family meal.


Ingredients

Scale

Beef Mixture

  • 1 lb ground beef
  • 1 small onion, chopped
  • 2 cloves garlic, minced
  • 1 tbsp olive oil
  • 1 can (10.5 oz) cream of mushroom soup
  • 1 can (10 oz) diced tomatoes with green chilies
  • 1 tsp salt
  • ½ tsp black pepper
  • ½ tsp paprika

Layering and Topping

  • 3 large potatoes, peeled and thinly sliced
  • 1 ½ cups shredded cheddar cheese
  • ½ cup sour cream
  • Fresh parsley, chopped (for garnish)


Instructions

  1. Preheat Oven: Preheat your oven to 375°F (190°C) and grease a 9×13-inch baking dish to prevent sticking.
  2. Cook Beef Mixture: Heat olive oil in a medium skillet over medium heat. Add the ground beef, chopped onion, and minced garlic. Cook until the beef is browned and onions are tender, stirring occasionally. Drain excess fat from the skillet.
  3. Combine Ingredients: Stir in the cream of mushroom soup, diced tomatoes with green chilies, salt, black pepper, and paprika into the beef mixture. Let it simmer for 5 minutes to meld the flavors, then remove from heat.
  4. First Potato Layer: Arrange half of the thinly sliced potatoes evenly on the bottom of the prepared baking dish, creating the base layer.
  5. First Beef Layer: Spread half of the seasoned beef mixture evenly over the potato layer.
  6. Cheese Layer: Sprinkle ½ cup of shredded cheddar cheese evenly over the beef layer.
  7. Second Potato Layer: Repeat by layering the remaining sliced potatoes over the cheese.
  8. Second Beef Layer: Spread the remaining beef mixture evenly on top of the potatoes.
  9. Final Cheese Layer: Top the casserole with the remaining shredded cheddar cheese for a cheesy crust.
  10. Bake Covered: Cover the baking dish with aluminum foil and bake in the preheated oven for 45 minutes to cook the potatoes through and heat the layers.
  11. Bake Uncovered: Remove the foil and continue baking for another 10-15 minutes until the cheese is melted, bubbly, and golden, and the potatoes are tender when pierced with a fork.
  12. Rest and Garnish: Let the casserole rest for 5 minutes to set. Serve topped with dollops of sour cream and a sprinkle of fresh chopped parsley for a fresh finish.

Notes

  • For a spicier kick, add a pinch of cayenne pepper to the beef mixture.
  • You can substitute cream of mushroom soup with cream of celery or cream of chicken soup for a different flavor profile.
  • Use Yukon Gold potatoes for a creamier texture or Russet potatoes for a firmer bite.
  • Allowing the casserole to rest after baking helps the layers set, making serving easier.
  • Leftovers can be stored covered in the refrigerator for up to 3 days and reheated in the oven.

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